At the dawn of the eighteenth century, while still a small boy, he was sent from his home in present-day Ghana to Amsterdam. From there he was sent to Germany as a court attendant of Duke Anton Ulrich of Braunschweig-Wolfenbüttel, and was subsequently baptized in 1708. He matriculated at the University of Halle in 1727, where he defended a law thesis. He then studied and taught at the University of Wittenberg, before returning to Halle to teach, and later also teaching in Jena. He returned to West Africa permanently in 1747.

Though much attention on and study of Amo has previously focused on his symbolic importance as a historical figure--the first African philosopher in modern Europe--Stephen Menn and Justin E. H. Smith argue for a serious engagement with Amo's work as a philosopher. In an extensive introduction, they contextualize his biography and writing within the surrounding intellectual and historical environment, and discuss and analyze his arguments in conversation with other philosophers of the time. This volume contains his two Wittenberg philosophical dissertations, On the Impassivity of the Human Mind and the Philosophical Disputation containing a Distinct Idea of those Things that Pertain either to the Mind or to our Living and Organic Body, both first published in 1734. The editors present the original Latin texts with side-by-side English translations and detailed explanatory annotations. In centering Amo's philosophical thought and making it accessible to more students and scholars, Menn
and Smith establish the originality and significance of Amo's rigorous contributions to the mind-body debate of the seventeenth and eighteenth centuries.