The effectiveness of the intervention of institutions and professionals in the fight against drugs fundamentally depends on the legislative and strategic bases established at European and national level. The activity of police and justice professionals, in order to prevent and combat illicit drug trafficking, is complemented by the activity of professionals in the field of preventing and combating illicit drug use, the consonant intervention of the social worker, psychologist, doctor and sociologist being crowned with success in a strategic, managerial and normative context very well built and permanently adjusted to the dynamics of social realities related to the drug situation.