Lately, Leona has led a stressful life. Her friends don't seem to trust her, her family's out roaming the streets with the rest of Zone Q's zombies, and, because of her recent contact with the Orb of the Zodiac, her fangs are coming in. Feeling less like a member of the Zodiac Dozen and more like a lion, it seems her struggles against the forces of evil will begin within.

Thankfully, she'll soon come to learn that even life's darkest times can be illuminated by the flames of friendship. Banding together with a few unlikely companions - including a king, an archer, and a girl with detachable hands - Leona devises a plan to finally end the invasion that's been plaguing Milwaukee. Their biggest obstacle? The rest of the Zodiac Dozen, who remain unconvinced that her idea will work. Without their support, Leona's forced to take matters into her own claws in a decision that could either reunite the Dozen or disband the group for good.

And, as can happen with the best of plans, Leona's comes with its own massive snag. Sure, she may have figured out how to convert a few zombies back to humans, but what she hadn't counted on was an all-new type of attack. The man on the back of the Moon has been busy, and he's ready to test the power of his new pet!