Myra Lipinsky is living a quiet life as a middle-aged, self-described spinster. She had been a lonely child, and now she is an equally lonely adult though she takes great pride in her career as a visiting nurse. Her patients are her only true emotional attachments, but when they are well, they move on.

When she gets a call about a new assignment, she is shocked to discover that the patient is Chip Reardon, a former high school classmate of Myra's. He had been the most popular and adored boy in school, but now he is suffering from an incurable brain tumor and plans to die at home. With their roles starkly reversed, Myra and Chip discover that it is often through facing death that we can truly begin to live.