This text is a collection of 26 experiments, observations, and other activities designed to accompany our text Life Science, an introductory biology text designed for sixth-grade students. The activities include a mixture of short items (10-15 min) and full-period (45-60 min) items. The Apprentice's Companion concept is unique: the book is a combination of experiment book, commonplace book, lab journal, and sketch book. Throughout the book are poems, historical connections, literary references, and artwork, all of which creates a delightful environment for students as they pursue practical studies in biology.